Structure of PDB 1ksf Chain X

Receptor sequence
>1ksfX (length=714) Species: 562 (Escherichia coli) [Search protein sequence]
MLNQELELSLNMAFARAREHRHEFMTVEHLLLALLSNPSAREALEACSVD
LVALRQELEAFIEQTTPVLPASEEERDTQPTLSFQRVLQRAVFHVQSSGR
NEVTGANVLVAIFSEQESQAAYLLRKHEVSRLDVVNFISHGTRLENFTTN
LNQLARVGGIDPLIGREKELERAIQVLCRRRKNNPLLVGESGVGKTAIAE
GLAWRIVQGDVPEVMADCTIYSLDIGAGTKYRGDFEKRFKALLKQLEQDT
NSILFIDEIHTIIGAGAASGGQVDAANLIKPLLSSGKIRVIGSTTYQEFS
NIFEKDRALARRFQKIDITEPSIEETVQIINGLKPKYEAHHDVRYTAKAV
RAAVELAVKYINDRHLPDKAIDVIDEAGARARLMPVSKRKKTVNVADIES
VVARIARIPEKSVSQSDRDTLKNLGDRLKMLVFGQDKAIEALTEAIKMAR
AGLGHEHKPVGSFLFAGPTGVGKTEVTVQLSKALGIELLRFDMSEYMERH
TVSRLIGAPPGYVGFDQGGLLTDAVIKHPHAVLLLDEIEKAHPDVFNILL
QVMDNGTLTDNNGRKADFRNVVLVMTTNAGVRNSTDAMEEIKKIFTPEFR
NRLDNIIWFDHLSTDVIHQVVDKFIVELQVQLDQKGVSLEVSQEARNWLA
EKGYDRAMGARPMARVIQDNLKKPLANELLFGSLVDGGQVTVALDKEKNE
LTYGFQSAQKHKAE
3D structure
PDB1ksf Crystal structure of ClpA, an HSP100 chaperone and regulator of ClpAP protease
ChainX
Resolution2.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MG X D520 S522 E565 D492 S494 E537
BS02 ADP X L188 I189 G217 G219 K220 T221 A222 I399 L163 I164 G192 G194 K195 T196 A197 I371
BS03 ADP X F461 G498 V499 G500 K501 T502 E503 V661 A701 F433 G470 V471 G472 K473 T474 E475 V620 A660
Gene Ontology
Molecular Function
GO:0004176 ATP-dependent peptidase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016887 ATP hydrolysis activity
Biological Process
GO:0006508 proteolysis
GO:0006515 protein quality control for misfolded or incompletely synthesized proteins
GO:0006979 response to oxidative stress
GO:0034605 cellular response to heat
GO:0043335 protein unfolding
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0009368 endopeptidase Clp complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1ksf, PDBe:1ksf, PDBj:1ksf
PDBsum1ksf
PubMed12205096
UniProtP0ABH9|CLPA_ECOLI ATP-dependent Clp protease ATP-binding subunit ClpA (Gene Name=clpA)

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