Structure of PDB 1h46 Chain X

Receptor sequence
>1h46X (length=431) [Search protein sequence]
EQAGTNTAENHPQLQSQQCTTSGGCKPLSTKVVLDSNWRWVHSTSGYTNC
YTGNEWDTSLCPDGKTCAANCALDGADYSGTYGITSTGTALTLKFVTGSN
VGSRVYLMADDTHYQLLKLLNQEFTFDVDMSNLPCGLNGALYLSAMDADG
GMSKYPGNKAGAKYGTGYCDSQCPKDIKFINGEANVGNWTETGSNTGTGS
YGTCCSEMDIWEANNDAAAFTPHPCTTTGQTRCSGDDCARNTGLCDGDGC
DFNSFRMGDKTFLGKGMTVDTSKPFTVVTQFLTNDNTSTGTLSEIRRIYI
QNGKVIQNSVANIPGVDPVNSITDNFCAQQKTAFGDTNWFAQKGGLKQMG
EALGNGMVLALSIWDDHAANMLWLDSDYPTDKDPSAPGVARGTCATTSGV
PSDVESQVPNSQVVFSNIKFGDIGSTFSGTS
3D structure
PDB1h46 The Catalytic Module of Cel7D from Phanerochaete Chrysosporium as a Chiral Selector: Structural Studies of its Complex with the Beta Blocker (R)-Propranolol
ChainX
Resolution1.52 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.2.1.-
3.2.1.4: cellulase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 RNP X Y142 D170 Q172 E207 D209 E212 R240 A369 W373 Y378 Y142 D170 Q172 E207 D209 E212 R240 A369 W373 Y378 MOAD: Ki=270uM
PDBbind-CN: -logKd/Ki=3.57,Ki=270uM
Gene Ontology
Molecular Function
GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds
Biological Process
GO:0005975 carbohydrate metabolic process

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:1h46, PDBe:1h46, PDBj:1h46
PDBsum1h46
PubMed12657782
UniProtQ7LHI2

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