Structure of PDB 6u42 Chain W5

Receptor sequence
>6u42W5 (length=427) Species: 3055 (Chlamydomonas reinhardtii) [Search protein sequence]
REVISIHIGQAGIQVGNACWELYCLEHGIQPDGQMPDAFNTFFSETGAGK
HVPRCIFLDLEPTVVDEVRTGTYRQLFHPEQLISGKEDAANNFARGHYTI
GKEIVDLALDRIRKLADNCTGLQGFLVFNAVGGGTGSGLGSLLLERLSVD
YGKKSKLGFTVYPSPQVSTAVVEPYNSVLSTHSLLEHTDVAVMLDNEAIY
DICRRSLDIERPTYTNLNRLIAQVISSLTASLRFDGALNVDITEFQTNLV
PYPRIHFMLSSYAPIISAEKAYHEQLSVAEITNAAFEPASMMVKCDPRHG
KYMACCLMYRGDVVPKDVNASVATIKTKRTIQFVDWCPTGFKCGINYQPP
TVVPGGDLAKVQRAVCMISNSTAIGEIFSRLDHKFDLMYAKRAFVHWYVG
EGMEEGEFSEAREDLAALEKDFEEVGA
3D structure
PDB6u42 Structure of the Decorated Ciliary Doublet Microtubule.
ChainW5
Resolution3.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.5.-
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 GTP W5 G10 Q11 A12 D98 A100 N101 G143 T145 T179 Y224 N228 G9 Q10 A11 D88 A90 N91 G133 T135 T169 Y214 N218
Gene Ontology
Molecular Function
GO:0005200 structural constituent of cytoskeleton
GO:0005525 GTP binding
GO:0016787 hydrolase activity
GO:0046872 metal ion binding
Biological Process
GO:0007010 cytoskeleton organization
GO:0007017 microtubule-based process
Cellular Component
GO:0005737 cytoplasm
GO:0005856 cytoskeleton
GO:0005874 microtubule

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:6u42, PDBe:6u42, PDBj:6u42
PDBsum6u42
PubMed31668805
UniProtP09204|TBA1_CHLRE Tubulin alpha-1 chain (Gene Name=TUBA1)

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