Structure of PDB 9gd3 Chain W

Receptor sequence

>9gd3W (length=864) Species: 559292 (Saccharomyces cerevisiae S288C)

PTRFSNRQNKTVNYNIDYSDDDLLDFHGIDIVINHRLKDLNNCKENYEFL
IKWTDESHLHNTWETYESIGQVRGLKRLDNYCKQFIIEDQQVRLDPYVTA
EDIEIMDMERERRLDEFEEFHVPERIIDSQRASLEDGTSQLQYLVKWRRL
NYDEATWENATDIVKLAPEQVKHFQNRENSKILPQYSSNYTSQRPRFEKL
SVQPPFIKGGELRDFQLTGINWMAFLWSKGDNGILADEMGLGKTVQTVAF
ISWLIFARRQNGPHIIVVPLSTMPAWLDTFEKWAPDLNCICYMGNQKSRD
TIREYEFYTNPRAKGKKTMKFNVLLTTYEYILKDRAELGSIKWQFMAVDE
AHRLKNAESSLYESLNSFKVANRMLITGTPLQNNIKELAALVNFLMPGRF
TIDQEIDFENQDEEQEEYIHDLHRRIQPFILRRLKKDVEKSLPSKTERIL
RVELSDVQTEYYKNILTKNYSALTAGAKGGHFSLLNIMNELKKASNHPYL
FDNAEERVLQKFGDGKMTRENVLRGLIMSSGKMVLLDQLLTRLKKDGHRV
LIFSQMVRMLDILGDYLSIKGINFQRLDGTVPSAQRRISIDHFNSPDSND
FVFLLSTRAGGLGINLMTADTVVIFDSDWNPQADLQAMARAHRIGQKNHV
MVYRLVSKDTVEEEVLERARKKMILEYAIIDMDSIGESEVRALYKAILKF
GNLKEILDELIADGTLPVKSFEKYGETYDEMMEAAKDCVHEEEKNRKVLF
NFKGVKSLNAESLLSRVEDLKYLKNLINSNYKDDPLKFSLGNNTPKPVQN
WSSNWTKEEDEKLLIGVFKYGYGSWTQIRDDPFLGITDKIFLKKVPGAIH
LGRRVDYLLSFLRG

3D structure

• PDB: 9gd3 Resolution of transcription-induced hexasome-nucleosome complexes by Chd1 and FACT.
• Chain: W
• Resolution: 3.0 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	dna	W	K497 L649 N650 N653 M720 G743 R750 S770 R772 A773	K333 L485 N486 N489 M556 G579 R586 S606 R608 A609
BS02	dna	W	N244 K478 R517 S523 S524 L525 W793 N794 R832 R1016 K1126 R1255	N80 K314 R353 S359 S360 L361 W629 N630 R668 R691 K756 R853
BS03	ADP	W	Q380 G404 L405 G406 K407 T408 V409 W447 N779 R807 I808	Q216 G240 L241 G242 K243 T244 V245 W283 N615 R643 I644
BS04	BEF	W	M403 G404 K407 R804 R807	M239 G240 K243 R640 R643
BS05	MG	W	D513 E514	D349 E350

External links

• PDB: RCSB:9gd3, PDBe:9gd3, PDBj:9gd3
• PDBsum: 9gd3
• PubMed: 39270644
• UniProt: P32657|CHD1_YEAST Chromo domain-containing protein 1 (Gene Name=CHD1)