Structure of PDB 9gd2 Chain W

Receptor sequence

>9gd2W (length=641) Species: 559292 (Saccharomyces cerevisiae S288C)

GIDIVINHRLLNNCKENYEFLIKWTDESHLHNTWETYESIGQVRGLKRLD
NYCKQFIIEDQQVRLDPYVTAEDIEIMDMERERRLDEFEEFHVPERIIDS
QRASLEDGTSQLQYLVKWRRLNYDEATWENATDIVKLAPEQVKHFQNREN
SKILPQYSSNYTSQRPRFEKLSVQPPFIKGGELRDFQLTGINWMAFLWSK
GDNGILADEMGLGKTVQTVAFISWLIFARRQNGPHIIVVPLSTMPAWLDT
FEKWAPDLNCICYMGNQKSRDTIREYEFYTNPKTMKFNVLLTTYEYILKD
RAELGSIKWQFMAVDEAHRLKNAESSLYESLNSFKVANRMLITGTPLQNN
IKELAALVNFLMPGRFTIDQEIDFENQDEEQEEYIHDLHRRIQPFILRRL
KKDVEKSLPSKTERILRVELSDVQTEYYKNILTKNYSALTAGFSLLNIMN
ELKKASNHPYLFDNAEERVLQKFGDGKMTRENVLRGLIMSSGKMVLLDQL
LTRLKKDGHRVLIFSQMVRMLDILGDYLSIKGINFQRLDGTVPSAQRRIS
IDHFNSPDSNDFVFLLSTRAGGLGINLMTADTVVIFDSDWNPQADLQAMA
RAHRIGQKNHVMVYRLVSKDTVEEEVLERARKKMILEYAII

3D structure

• PDB: 9gd2 Resolution of transcription-induced hexasome-nucleosome complexes by Chd1 and FACT.
• Chain: W
• Resolution: 4.2 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	dna	W	N459 E493 Y494 M720 V721 G743 R750 S770 R772 A773	N266 E295 Y296 M517 V518 G540 R547 S567 R569 A570
BS02	dna	W	R241 N244 R517 K519 S523 S524 W793 R832	R48 N51 R319 K321 S325 S326 W590 R629
BS03	peptide	W	K393 G394 D395 T565 R589	K200 G201 D202 T367 R391
BS04	ADP	W	E375 L376 R377 Q380 G404 G406 K407 T408 V409 W447 R807 I808	E182 L183 R184 Q187 G211 G213 K214 T215 V216 W254 R604 I605
BS05	BEF	W	M403 G404 K407 R804 R807	M210 G211 K214 R601 R604

External links

• PDB: RCSB:9gd2, PDBe:9gd2, PDBj:9gd2
• PDBsum: 9gd2
• PubMed: 39270644
• UniProt: P32657|CHD1_YEAST Chromo domain-containing protein 1 (Gene Name=CHD1)