Structure of PDB 8szn Chain W

Receptor sequence
>8sznW (length=190) Species: 487 (Neisseria meningitidis) [Search protein sequence]
TVIEQSGRGERAFDIYSRLLKERIVFLVGPVTDESANLVVAQLLFLESEN
PDKDIFFYINSPGGSVTAGMSIYDTMNFIKPDVSTLCLGQAASMGAFLLS
AGEKGKRFALPNSRIMIHQPLISGGGQASDIEIHARELLKIKEKLNRLMA
KHCDRDLADLERDTDRDNFMSAEEAKEYGLIDQILENRAS
3D structure
PDB8szn Structure-Based Design and Development of Phosphine Oxides as a Novel Chemotype for Antibiotics that Dysregulate Bacterial ClpP Proteases.
ChainW
Resolution2.33 Å
3D
structure
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Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 X3O W R27 L28 E31 I33 F65 Y67 L95 F117 R199 R18 L19 E22 I24 F56 Y58 L86 F108 R188
BS02 X3O W L53 F54 S57 F87 L44 F45 S48 F78
External links
PDB RCSB:8szn, PDBe:8szn, PDBj:8szn
PDBsum8szn
PubMed39221504
UniProtQ9JZ38|CLPP_NEIMB ATP-dependent Clp protease proteolytic subunit (Gene Name=clpP)

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