Structure of PDB 8s55 Chain W

Receptor sequence
>8s55W (length=187) Species: 9606 (Homo sapiens) [Search protein sequence]
VPAALKRLAKYVIRGFYGIEHALALDILIRNSCVKEEDMLELLKFDRKQL
RSVLNNLKGDKFIKCRMRVETAADGKTTRHNYYFINYRTLVNVVKYKLDH
MRRRIETDERDSTNRASFKCPVCSSTFTDLEANQLFDPMTGTFRCTFCHT
EVEEDESAMPKKDARTLLARFNEQIEPIYALLRETED
3D structure
PDB8s55 Three-step mechanism of promoter escape by RNA polymerase II
ChainW
Resolution3.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN W C129 C154 C120 C145
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0016251 RNA polymerase II general transcription initiation factor activity
GO:0046872 metal ion binding
Biological Process
GO:0001113 transcription open complex formation at RNA polymerase II promoter
GO:0006366 transcription by RNA polymerase II
GO:0006367 transcription initiation at RNA polymerase II promoter
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005669 transcription factor TFIID complex
GO:0005673 transcription factor TFIIE complex
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8s55, PDBe:8s55, PDBj:8s55
PDBsum8s55
PubMed38604172
UniProtP29083|T2EA_HUMAN General transcription factor IIE subunit 1 (Gene Name=GTF2E1)

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