Structure of PDB 8rt7 Chain W

Receptor sequence

>8rt7W (length=246) Species: 562 (Escherichia coli) [Search protein sequence]

LDVPSSSRYDHRIRYVTYNPADVVQVDTVLGVATHIMLEEGEQYLTHAFG
DSEAYAFARKGRHIFIKPQAELANTNLIVVTDRRSYKFRLQMRNDRNGAM
YELAFRYPDTQARQTREANARAAVEAAFEQRVGAYYNLKYMMSGDKDIAP
VNAWDDGRFTYFKFSANADLPSIYFVDAEGNESLVPRTTVGSSNNIIAVH
KVNPKWMIRLGNRALAIFNEAYDPNGVPNDTGTASPAVRRVNKGGN

3D structure

PDB

8rt7 Cryo-EM structure of a conjugative type IV secretion system suggests a molecular switch regulating pilus biogenesis.

Chain

Resolution

2.93 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	peptide	W	Y156 L158 Y160 M161 M162 S163 G164 D165 K166 N172 A173 W174 K183 M227 R229 A234 F238 E240	Y136 L138 Y140 M141 M142 S143 G144 D145 K146 N152 A153 W154 K163 M207 R209 A214 F218 E220
BS02	peptide	W	L50 A76 F85 K87 Q89 A90 E91 R116	L30 A56 F65 K67 Q69 A70 E71 R96

External links

PDB	RCSB:8rt7, PDBe:8rt7, PDBj:8rt7
PDBsum	8rt7
PubMed	38886579
UniProt	O50336

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