Structure of PDB 8c90 Chain W

Receptor sequence
>8c90W (length=70) Species: 562 (Escherichia coli) [Search protein sequence]
SEAKRLGVKRFGGESVLAGSIIVRQRGTKFHAGANVGCGRDHTLFAKADG
KVKFEVKGPKNRKFISIEAE
3D structure
PDB8c90 Cryo-EM captures early ribosome assembly in action.
ChainW
Resolution3.15 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 rna W S12 E13 A14 R16 R21 F22 G23 E25 A29 G30 I32 R35 R37 G38 T39 K40 G50 R51 D52 H53 F56 K71 R73 K74 S1 E2 A3 R5 R10 F11 G12 E14 A18 G19 I21 R24 R26 G27 T28 K29 G39 R40 D41 H42 F45 K60 R62 K63
BS02 rna W P70 N72 P59 N61
Gene Ontology
Molecular Function
GO:0000049 tRNA binding
GO:0003735 structural constituent of ribosome
GO:0005515 protein binding
GO:0019843 rRNA binding
GO:0043022 ribosome binding
Biological Process
GO:0000027 ribosomal large subunit assembly
GO:0001558 regulation of cell growth
GO:0002181 cytoplasmic translation
GO:0006412 translation
GO:0042256 cytosolic ribosome assembly
GO:0090070 positive regulation of ribosome biogenesis
GO:1902626 assembly of large subunit precursor of preribosome
Cellular Component
GO:0005737 cytoplasm
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Molecular Function

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Cellular Component
External links
PDB RCSB:8c90, PDBe:8c90, PDBj:8c90
PDBsum8c90
PubMed36797249
UniProtP0A7L8|RL27_ECOLI Large ribosomal subunit protein bL27 (Gene Name=rpmA)

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