Structure of PDB 8c8x Chain W

Receptor sequence
>8c8xW (length=76) Species: 562 (Escherichia coli) [Search protein sequence]
TRNGRDSEAKRLGVKRFGGESVLAGSIIVRQRGTKFHAGANVGCGRDHTL
FAKADGKVKFEVKGPKNRKFISIEAE
3D structure
PDB8c8x Cryo-EM captures early ribosome assembly in action.
ChainW
Resolution3.93 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna W T1 R2 N3 R5 S7 E8 R11 K15 F17 E20 L23 A24 G25 I27 R30 R32 T34 K35 R46 D47 H48 F51 K59 F60 R68 T1 R2 N3 R5 S7 E8 R11 K15 F17 E20 L23 A24 G25 I27 R30 R32 T34 K35 R46 D47 H48 F51 K59 F60 R68
BS02 rna W V62 K63 G64 P65 N67 V62 K63 G64 P65 N67
Gene Ontology
Molecular Function
GO:0000049 tRNA binding
GO:0003735 structural constituent of ribosome
GO:0005515 protein binding
GO:0019843 rRNA binding
GO:0043022 ribosome binding
Biological Process
GO:0000027 ribosomal large subunit assembly
GO:0001558 regulation of cell growth
GO:0002181 cytoplasmic translation
GO:0006412 translation
GO:0042256 cytosolic ribosome assembly
GO:0090070 positive regulation of ribosome biogenesis
GO:1902626 assembly of large subunit precursor of preribosome
Cellular Component
GO:0005737 cytoplasm
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8c8x, PDBe:8c8x, PDBj:8c8x
PDBsum8c8x
PubMed36797249
UniProtP0A7L8|RL27_ECOLI Large ribosomal subunit protein bL27 (Gene Name=rpmA)

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