Structure of PDB 8a5q Chain W

Receptor sequence
>8a5qW (length=433) Species: 209285 (Thermochaetoides thermophila) [Search protein sequence]
ADIYGGDEVSALVLDPGYCNTRAGFAGEEMPKQVIPSFYGHVDGRDLFGD
EVIVPRAGFEVRNYMNRDSMVEDWDAATRVWEYLLVQRLQPPRPTPASKN
GLNVKPLTENPLLMTEAPWNTPKAREKAIEVVMENWGTPAFWLSRTPVLA
AFAAGKATALVIDVGGANTSVTAIHDGMVLKRSIQRSPAAGVWLSGQIRS
MWKSQDPPVNVVPTFMVENKKPVEAGAPPDCRLRNFGFPIHDSFRAFEEE
RVLTEFKESVVEVWRGPGKYLNPGNEDFAKTQPGRVFEFPDGSNQMWREQ
RYRVAEGMWDETAAYPSLNPDEAAITKAQTIPALIKAALDGVDVDLRPNL
LGNVVVTGSTSLLNGFNDRLNHELTNMYPGLKIKLHAAGLTSERRFGAWI
GGSILASLGTFHQMWISRKEYEENGAGIVEKRC
3D structure
PDB8a5q Structural mechanism of extranucleosomal DNA readout by the INO80 complex.
ChainW
Resolution3.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 ATP W Y30 C31 R34 S81 G199 G200 G225 T288 K291 E292 S393 Y18 C19 R22 S69 G165 G166 G191 T254 K257 E258 S359
Gene Ontology
Molecular Function
GO:0003682 chromatin binding
Biological Process
GO:0006281 DNA repair
GO:0006357 regulation of transcription by RNA polymerase II
Cellular Component
GO:0016514 SWI/SNF complex
GO:0035267 NuA4 histone acetyltransferase complex

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:8a5q, PDBe:8a5q, PDBj:8a5q
PDBsum8a5q
PubMed36490333
UniProtG0SBW4

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