Structure of PDB 8a5a Chain W

Receptor sequence
>8a5aW (length=427) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence]
LQVYGGDEVSAVVIDPGSYTTNIGYSGSDFPQSILPSVYGKYTADEGNKK
IFSEQSIGIPRKDYELKPIIENGLVIDWDTAQEQWQWALQNELYLNSNSG
IPALLTEPVWNSTENRKKSLEVLLEGMQFEACYLAPTSTCVSFAAGRPNC
LVVDIGHDTCSVSPIVDGMTLSKSTRRNFIAGKFINHLIKKALEPKEIIP
LFAIKQRKPEFIKKTFDYEVDKSLYDYANNRGFFQECKETLCHICPTKTL
EETKTELSSTAKRSIESPWNEEIVFDNETRYGFAEELFLPKEDDIPANWP
RSNSGVVKTWRNDYVPLKELIGLADLVYSSIMSSDVDLRATLAHNVVLTG
GTSSIPGLSDRLMTELNKILPSLKFRILTTGHTIERQYQSWLGGSILTSL
GTFHQLWVGKKEYEEVGVERLLNDRFR
3D structure
PDB8a5a Structural mechanism of extranucleosomal DNA readout by the INO80 complex.
ChainW
Resolution3.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ATP W G22 S23 Y24 H162 T164 Q240 K243 G413 T414 Q449 G17 S18 Y19 H157 T159 Q235 K238 G351 T352 Q387
Gene Ontology
Molecular Function
GO:0003682 chromatin binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0042393 histone binding
Biological Process
GO:0006281 DNA repair
GO:0006325 chromatin organization
GO:0006338 chromatin remodeling
GO:0006351 DNA-templated transcription
GO:0006355 regulation of DNA-templated transcription
GO:0006357 regulation of transcription by RNA polymerase II
GO:0051382 kinetochore assembly
Cellular Component
GO:0000785 chromatin
GO:0000812 Swr1 complex
GO:0005634 nucleus
GO:0016514 SWI/SNF complex
GO:0031011 Ino80 complex
GO:0035267 NuA4 histone acetyltransferase complex
GO:0043232 intracellular non-membrane-bounded organelle

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8a5a, PDBe:8a5a, PDBj:8a5a
PDBsum8a5a
PubMed36490333
UniProtP80428|ARP4_YEAST Actin-related protein 4 (Gene Name=ARP4)

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