Structure of PDB 7rh7 Chain W

Receptor sequence

>7rh7W (length=158) Species: 246196 (Mycolicibacterium smegmatis MC2 155) [Search protein sequence]

CSAGQISQTTTQEPAVNGVNAQAGQVSLRNVHLRAPQQTDYVEPGTTVEL
LFVAANDSTESNKLKSITSDVGEVTLTGDSTVPADGVLIVGEPDGQIQAV
ENAEAADAVTAEVELTKPITNGLLYDFTFTFEDGETTVAVPISAGEQPRR
PVPPAGPG

3D structure

PDB

7rh7 Structure of mycobacterial CIII 2 CIV 2 respiratory supercomplex bound to the tuberculosis drug candidate telacebec (Q203).

Chain

Resolution

3.0 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	9Y0	W	Q28 I29	Q5 I6
BS02	HEC	W	Q35 A38	Q12 A15

External links

PDB	RCSB:7rh7, PDBe:7rh7, PDBj:7rh7
PDBsum	7rh7
PubMed	34590581
UniProt	A0R562

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