Structure of PDB 7pjy Chain W

Receptor sequence

>7pjyW (length=75) Species: 83333 (Escherichia coli K-12)

RNGRDSEAKRLGVKRFGGESVLAGSIIVRQRGTKFHAGANVGCGRDHTLF
AKADGKVKFEVKGPKNRKFISIEAE

3D structure

• PDB: 7pjy Structural mechanism of GTPase-powered ribosome-tRNA movement.
• Chain: W
• Resolution: 3.1 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	W	R7 N8 R10 D11 S12 E13 A14 K15 R16 L17 K20 F22 G23 E25 L28 A29 G30 S31 I32 R37 G38 T39 K40 F41 H42 G50 R51 D52 H53 T54 F56 F65 R73 K74	R1 N2 R4 D5 S6 E7 A8 K9 R10 L11 K14 F16 G17 E19 L22 A23 G24 S25 I26 R31 G32 T33 K34 F35 H36 G44 R45 D46 H47 T48 F50 F59 R67 K68
BS02	rna	W	G69 P70 N72	G63 P64 N66

Gene Ontology

Molecular Function

• GO:0000049 tRNA binding
• GO:0003735 structural constituent of ribosome
• GO:0005515 protein binding
• GO:0019843 rRNA binding
• GO:0043022 ribosome binding

Biological Process

• GO:0000027 ribosomal large subunit assembly
• GO:0001558 regulation of cell growth
• GO:0002181 cytoplasmic translation
• GO:0006412 translation
• GO:0042256 cytosolic ribosome assembly
• GO:0090070 positive regulation of ribosome biogenesis
• GO:1902626 assembly of large subunit precursor of preribosome

Cellular Component

• GO:0005737 cytoplasm
• GO:0005840 ribosome
• GO:0022625 cytosolic large ribosomal subunit
• GO:1990904 ribonucleoprotein complex

External links

• PDB: RCSB:7pjy, PDBe:7pjy, PDBj:7pjy
• PDBsum: 7pjy
• PubMed: 34635670
• UniProt: P0A7L8|RL27_ECOLI Large ribosomal subunit protein bL27 (Gene Name=rpmA)