Structure of PDB 7o75 Chain W

Receptor sequence
>7o75W (length=312) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence]
DRPIDDIVKNLLKFVVRGFYGGSFVLVLDAILFHSVLAEDDLKQLLSINK
TELGPLIARLRSDRLISIHKQREYPPNSKSVERVYYYVKYPHAIDAIKWK
VHQVVQRLKDDLDKNSEPNGYMCPICLTKYTQLEAVQLLNFDRTEFLCSL
CDEPLVEDDSGKKNKEKQDKLNRLMDQIQPIIDSLKKIDDSRIEENTFEI
ALARLIPPQNQSHAAYTYNPKKGSTMFRPGDSAPATLHINITTASDEVAQ
RELQERQAEEKRKQNAVPEWHKQSTIGKTALGREERENEKTLNDYYAALA
KKQALEDEFEDV
3D structure
PDB7o75 Structure of RNA polymerase II pre-initiation complex at 2.9 angstrom defines initial DNA opening.
ChainW
Resolution3.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN W C124 C127 C149 C152 C123 C126 C148 C151
Gene Ontology
Molecular Function
GO:0000993 RNA polymerase II complex binding
GO:0001097 TFIIH-class transcription factor complex binding
GO:0003697 single-stranded DNA binding
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0046872 metal ion binding
Biological Process
GO:0001113 transcription open complex formation at RNA polymerase II promoter
GO:0006366 transcription by RNA polymerase II
GO:0006367 transcription initiation at RNA polymerase II promoter
Cellular Component
GO:0005634 nucleus
GO:0005673 transcription factor TFIIE complex
GO:0005739 mitochondrion
GO:0097550 transcription preinitiation complex

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Cellular Component
External links
PDB RCSB:7o75, PDBe:7o75, PDBj:7o75
PDBsum7o75
PubMed34133942
UniProtP36100|T2EA_YEAST Transcription initiation factor IIE subunit alpha (Gene Name=TFA1)

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