Structure of PDB 7ko7 Chain W

Receptor sequence
>7ko7W (length=274) Species: 9823 (Sus scrofa) [Search protein sequence]
LKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKY
SEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATAL
QKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADR
KYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQ
AEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDEL
YAQKLKYKAISEELDHALNDMTSI
3D structure
PDB7ko7 The structure of the native cardiac thin filament at systolic Ca 2+ levels.
ChainW
Resolution8.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide W L278 M281 S283 I284 L268 M271 S273 I274
BS02 peptide W T282 I284 T272 I274
Gene Ontology
Molecular Function
GO:0003779 actin binding
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
GO:0046982 protein heterodimerization activity
GO:0051015 actin filament binding
Biological Process
GO:0007015 actin filament organization
GO:0060048 cardiac muscle contraction
Cellular Component
GO:0005737 cytoplasm
GO:0005856 cytoskeleton
GO:0005884 actin filament
GO:0015629 actin cytoskeleton

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7ko7, PDBe:7ko7, PDBj:7ko7
PDBsum7ko7
PubMed33753506
UniProtP42639|TPM1_PIG Tropomyosin alpha-1 chain (Gene Name=TPM1)

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