Structure of PDB 6pbs Chain W

Receptor sequence
>6pbsW (length=147) Species: 1773 (Mycobacterium tuberculosis) [Search protein sequence]
MFERFTDRARRVVVLAQEEARMLNHNYIGTEHILLGLIHEGEGVAAKSLE
SLGISLEGVRSQVEEIIGQGQQAPSGHIPFTPRAKKVLELSLREALQLGH
NYIGTEHILLGLIREGEGVAAQVLVKLGAELTRVRQQVIQLLSGYKL
3D structure
PDB6pbs Structure of the N-terminal domain of ClpC1 in complex with the antituberculosis natural product ecumicin reveals unique binding interactions.
ChainW
Resolution2.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide W G144 Y145 L147 G144 Y145 L147
BS02 peptide W Q17 H77 F80 K85 L88 Q17 H77 F80 K85 L88
BS03 peptide W M1 F2 E3 F5 R10 E89 L92 L96 M1 F2 E3 F5 R10 E89 L92 L96
External links
PDB RCSB:6pbs, PDBe:6pbs, PDBj:6pbs
PDBsum6pbs
PubMed32355042
UniProtP9WPC9|CLPC1_MYCTU ATP-dependent Clp protease ATP-binding subunit ClpC1 (Gene Name=clpC1)

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