Structure of PDB 6n8o Chain W

Receptor sequence
>6n8oW (length=377) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence]
NEQRGNLNAKQRALAKDLIVPRRPEWNEGMSKFQLDRQEKEAFLEWRRKL
AHLQESNEDLLLTPFERNIEVWKQLWRVVERSDLVVQIVDARNPLLFRSV
DLERYVKESDDRKANLLLVNKADLLTKKQRIAWAKYFISKNISFTFYSAL
RANQLLEVKILSIDQLEELFLSKAPNEPLLPPLPGQPPLINIGLVGYPNV
GKSSTINSLVGAKKVSVSSTPGKTKHFQTIKLSDSVMLCDCPGLVFPNFA
YNKGELVCNGVLPIDQLRDYIGPAGLVAERIPKYYIEAIYGIHIQTKSRD
EGGNGDIPTAQELLVAYARARGYMTQGYGSADEPRASRYILKDYVNGKLL
YVNPPPHLEDDTPYTREECEEFNKDLY
3D structure
PDB6n8o Tightly-orchestrated rearrangements govern catalytic center assembly of the ribosome.
ChainW
Resolution3.5 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 3.6.1.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna W W142 R193 E196 K360 K361 S363 T367 F374 Q375 T376 D412 Q413 R415 R468 G469 T472 Q473 G474 P481 R485 W26 R77 E80 K213 K214 S216 T220 F227 Q228 T229 D265 Q266 R268 R321 G322 T325 Q326 G327 P334 R338
Gene Ontology
Molecular Function
GO:0003729 mRNA binding
GO:0003924 GTPase activity
GO:0005515 protein binding
GO:0005525 GTP binding
GO:0016787 hydrolase activity
Biological Process
GO:0000027 ribosomal large subunit assembly
GO:0000054 ribosomal subunit export from nucleus
GO:0015031 protein transport
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0022625 cytosolic large ribosomal subunit
GO:0043332 mating projection tip

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:6n8o, PDBe:6n8o, PDBj:6n8o
PDBsum6n8o
PubMed30814529
UniProtP53145|LSG1_YEAST Large subunit GTPase 1 (Gene Name=LSG1)

[Back to BioLiP]