Structure of PDB 6j50 Chain W

Receptor sequence
>6j50W (length=275) Species: 644223 (Komagataella phaffii GS115) [Search protein sequence]
PQRLLIPTVDDPGIWGVKVRLGKEKDVVRQILKKKLAREGTKNPLEIYSA
FQRDSFKGHVYIEARKAEAINDALKGNVNVFSNNSKFLVGIVEYKDLLRP
VKLTRGSYVRVKNGKFKGDLAQVDEVLENGLEARLKLVPRLDYGKDLSYT
SKFRPAQRLFSEAEARVHEIRRDRDGFVTYGGEEYYEGFLYKTFRLQNLI
VNSINPTLNELSLFDPTLNKTVKIRQGGYKGKIGIVKEANGDRFRVELHN
PNKTIPIPCSFLLIESTHGWVPYED
3D structure
PDB6j50 Structural insight into nucleosome transcription by RNA polymerase II with elongation factors.
ChainW
Resolution4.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 dna W N330 N434 N113 N198
BS02 dna W K334 K386 K117 K152
BS03 dna W K278 A279 E280 L300 K66 A67 E68 L88
Gene Ontology
Molecular Function
GO:0003711 transcription elongation factor activity
GO:0003729 mRNA binding
GO:0140463 chromatin-protein adaptor activity
Biological Process
GO:0006325 chromatin organization
GO:0006354 DNA-templated transcription elongation
GO:0006357 regulation of transcription by RNA polymerase II
GO:0006368 transcription elongation by RNA polymerase II
GO:0032784 regulation of DNA-templated transcription elongation
Cellular Component
GO:0005634 nucleus
GO:0032044 DSIF complex

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Biological Process

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Cellular Component
External links
PDB RCSB:6j50, PDBe:6j50, PDBj:6j50
PDBsum6j50
PubMed30733384
UniProtC4R370

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