Structure of PDB 6ezj Chain W

Receptor sequence
>6ezjW (length=185) Species: 3702 (Arabidopsis thaliana) [Search protein sequence]
RIGEVKRETKETNVSVKINLDGHGVSDSSTGIPFLDHMLDQLASHGLFDV
HVRATGDTHIDDHHTNEDVALAIGTALLKALGERKGINRFGDFTAPLDEA
LIHVSLDLSGRPYLGYNLEIPTQRVGTYDTQLVEHFFQSLVNTSGMTLHI
RQLAGKNSHHIIEATFKAFARALRQATESDPRRGG
3D structure
PDB6ezj Elucidating the structural basis for differing enzyme inhibitor potency by cryo-EM.
ChainW
Resolution3.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 4.2.1.19: imidazoleglycerol-phosphate dehydratase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 5LD W H73 E77 H63 E67
BS02 MN W H73 E77 H145 H63 E67 H135
BS03 MN W H47 H169 E173 H37 H159 E163
BS04 5LD W H169 H170 E173 H159 H160 E163
Gene Ontology
Molecular Function
GO:0004424 imidazoleglycerol-phosphate dehydratase activity
Biological Process
GO:0000105 L-histidine biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:6ezj, PDBe:6ezj, PDBj:6ezj
PDBsum6ezj
PubMed29434040
UniProtO23346|HIS5B_ARATH Imidazoleglycerol-phosphate dehydratase 2, chloroplastic (Gene Name=HISN5B)

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