Structure of PDB 4toa Chain W

Receptor sequence
>4toaW (length=154) Species: 208964 (Pseudomonas aeruginosa PAO1) [Search protein sequence]
GDKKVIQHLNKILGNELIAINQYFLHSRMWNDWGLKRLGAHEYHESIDEM
KHADKLIERILFLEGLPNLQDLGKLLIGENTQEMLQCDLNLELKATKDLR
EAIVHCEQVHDYVSRDLLKDILESEEEHIDYLETQLGLIQKVGLELYLQS
HMHE
3D structure
PDB4toa Concerted motions networking pores and distant ferroxidase centers enable bacterioferritin function and iron traffic.
ChainW
Resolution1.95 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.16.3.1: ferroxidase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FE2 W E18 E51 H54 E127 E16 E49 H52 E125
BS02 FE2 W H10 H107 H8 H105
BS03 FE2 W E51 E94 E127 H130 E49 E92 E125 H128
BS04 FE2 W K121 E125 K119 E123
BS05 HEM W L19 I22 F26 I49 M52 K53 L17 I20 F24 I47 M50 K51
Gene Ontology
Molecular Function
GO:0004322 ferroxidase activity
GO:0005506 iron ion binding
GO:0008199 ferric iron binding
GO:0015093 ferrous iron transmembrane transporter activity
GO:0016491 oxidoreductase activity
GO:0020037 heme binding
GO:0046872 metal ion binding
Biological Process
GO:0006826 iron ion transport
GO:0006879 intracellular iron ion homeostasis
GO:0006880 intracellular sequestering of iron ion
GO:0034755 iron ion transmembrane transport
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0070288 ferritin complex

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Molecular Function
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Cellular Component
External links
PDB RCSB:4toa, PDBe:4toa, PDBj:4toa
PDBsum4toa
PubMed25640193
UniProtQ9HY79

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