Structure of PDB 3cx5 Chain W

Receptor sequence

>3cx5W (length=108) Species: 559292 (Saccharomyces cerevisiae S288C)

TEFKAGSAKKGATLFKTRCLQCHTVEKGGPHKVGPNLHGIFGRHSGQAEG
YSYTDANIKKNVLWDENNMSEYLTNPKKYIPGTKMAFGGLKKEKDRNDLI
TYLKKACE

3D structure

• PDB: 3cx5 Structure of complex III with bound cytochrome c in reduced state and definition of a minimal core interface for electron transfer.
• Chain: W
• Resolution: 1.9 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	HEM	W	R18 C19 Q21 C22 H23 V33 G34 P35 L37 I40 S45 G46 Y51 Y53 T54 N57 M69 L73 T83 K84 M85 F87	R18 C19 Q21 C22 H23 V33 G34 P35 L37 I40 S45 G46 Y51 Y53 T54 N57 M69 L73 T83 K84 M85 F87

Gene Ontology

Molecular Function

• GO:0005515 protein binding
• GO:0009055 electron transfer activity
• GO:0020037 heme binding
• GO:0046872 metal ion binding
• GO:1901612 cardiolipin binding

Biological Process

• GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c
• GO:0006123 mitochondrial electron transport, cytochrome c to oxygen

Cellular Component

• GO:0005739 mitochondrion
• GO:0005758 mitochondrial intermembrane space

External links

• PDB: RCSB:3cx5, PDBe:3cx5, PDBj:3cx5
• PDBsum: 3cx5
• PubMed: 18390544
• UniProt: P00044|CYC1_YEAST Cytochrome c isoform 1 (Gene Name=CYC1)