Structure of PDB 7a5f Chain V6

Receptor sequence
>7a5fV6 (length=328) Species: 9606 (Homo sapiens) [Search protein sequence]
DSHKWEAREKEHYCLADLASLMDKTFERKLPVSSLTISRLIDNISSREEI
DHAEYYLYKFRHSPNCWYLRNWTIHTWIRQCLKYDAQDKALYTLVNKVQY
GIFPDNFTFNLLMDSFIKKENYKDALSVVFEVMMQEAFEVPSTQLLSLYV
LFHCLAKKTDFSWEEERNFGASLLLPGLKQKNSVGFSSQLYGYALLGKVE
LQQGLRAVYHNMPLIWKPGYLDRALQVMEKVAASEALDVLGAVLKALTKL
VEQLDIEETEQSKLPQYLERFKALHSKLQALGLTTQLVKEKLSTCEAEDI
ATYEQNLQQWHLDLVQLIQREQQQREQA
3D structure
PDB7a5f Elongational stalling activates mitoribosome-associated quality control.
ChainV6
Resolution4.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna V6 L65 P66 S68 W102 Y103 R105 R392 Q396 L30 P31 S33 W67 Y68 R70 R320 Q324
Gene Ontology
Molecular Function
GO:0000049 tRNA binding
GO:0005515 protein binding
GO:0019843 rRNA binding
GO:0097177 mitochondrial ribosome binding
Biological Process
GO:0006417 regulation of translation
GO:0008283 cell population proliferation
GO:0032543 mitochondrial translation
GO:0070131 positive regulation of mitochondrial translation
Cellular Component
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005763 mitochondrial small ribosomal subunit
GO:0005840 ribosome
GO:1990904 ribonucleoprotein complex

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Cellular Component
External links
PDB RCSB:7a5f, PDBe:7a5f, PDBj:7a5f
PDBsum7a5f
PubMed33243891
UniProtQ92552|RT27_HUMAN Small ribosomal subunit protein mS27 (Gene Name=MRPS27)

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