Structure of PDB 9ft0 Chain V

Receptor sequence
>9ft0V (length=221) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence]
TIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAGAGTAAD
TEAVTQLIGSNIELHSLYTSREPRVVSALQMLKQHLFKYQGHIGAYLIVA
GVDPTGSHLFSIHAHGSTDVGYYLSLGSGSLAAMAVLESHWKQDLTKEEA
IKLASDAIQAGIWNDLGSGSNVDVCVMEIGKDAEYLRNYLTPNVREEKQK
SYKFPRGTTAVLKESIVNICD
3D structure
PDB9ft0 Structure-based design of peptide epoxyketones selectively targeting the three human immunoproteasome active sites
ChainV
Resolution2.75 Å
3D
structure
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Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 MG V I163 D166 S169 I162 D165 S168
BS02 A1IFL V T2 D17 S20 T21 K33 A46 G47 T48 A49 G128 S129 G168 S169 T1 D16 S19 T20 K32 A45 G46 T47 A48 G127 S128 G167 S168
External links
PDB RCSB:9ft0, PDBe:9ft0, PDBj:9ft0
PDBsum9ft0
PubMed
UniProtP25043|PSB2_YEAST Proteasome subunit beta type-2 (Gene Name=PUP1)

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