Structure of PDB 8wdk Chain V

Receptor sequence
>8wdkV (length=155) Species: 9606 (Homo sapiens) [Search protein sequence]
PRPVLRSVNSREPSQVIFCNRSPRVVLPVWLNFDGEPQPYPTLPPGTGRR
IHSYRGHLWLFRDAGTHDGLLVNQTELFVPSLNVDGQPIFANITLPVYTL
KERCLQVVRSLVKPENYRRLDIVRSLYEDLEDHPNVQKDLERLTQERIAH
QRMGD
3D structure
PDB8wdk Structure of Cul2-VCB-Protac-Wee1 complex at 3.6 Angstrom resolution.
ChainV
Resolution3.64 Å
3D
structure
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Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 W6U V R69 W88 F91 Y98 P99 R107 I109 H110 S111 Y112 H115 R11 W30 F33 Y40 P41 R49 I51 H52 S53 Y54 H57
External links
PDB RCSB:8wdk, PDBe:8wdk, PDBj:8wdk
PDBsum8wdk
PubMed
UniProtP40337|VHL_HUMAN von Hippel-Lindau disease tumor suppressor (Gene Name=VHL)

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