Structure of PDB 8qrm Chain V

Receptor sequence
>8qrmV (length=362) Species: 9606 (Homo sapiens) [Search protein sequence]
LLSSAYVDSHKWEAREKEHYCLADLASLMDKTFERKLPVSSLTISRLIDN
ISSREEIDHAEYYLYKFRHSPNCWYLRNWTIHTWIRQCLKYDAQDKALYT
LVNKVQYGIFPDNFTFNLLMDSFIKKENYKDALSVVFEVMMQEAFEVPST
QLLSLYVLFHCLAKKTDFSWEEERNFGASLLLPGLKQKNSVGFSSQLYGY
ALLGKVELQQGLRAVYHNMPLIWKPGYLDRALQVMEKVAASPEDIKLCRE
ALDVLGAVLKALTSAEKLVEQLDIEETEQSKLPQYLERFKALHSKLQALG
KIESEGLLSLTTQLVKEKLSTCEAEDIATYEQNLQQWHLDLVQLIQREQQ
QREQAKQEYQAQ
3D structure
PDB8qrm GTPBP8 plays a role in mitoribosome formation in human mitochondria.
ChainV
Resolution3.05 Å
3D
structure
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Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna V K64 P66 S68 S69 N100 W102 Y103 R105 R392 Q396 K36 P38 S40 S41 N72 W74 Y75 R77 R347 Q351
Gene Ontology
Molecular Function
GO:0000049 tRNA binding
GO:0005515 protein binding
GO:0019843 rRNA binding
GO:0097177 mitochondrial ribosome binding
Biological Process
GO:0006417 regulation of translation
GO:0008283 cell population proliferation
GO:0032543 mitochondrial translation
GO:0070131 positive regulation of mitochondrial translation
Cellular Component
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005763 mitochondrial small ribosomal subunit
GO:0005840 ribosome
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8qrm, PDBe:8qrm, PDBj:8qrm
PDBsum8qrm
PubMed38969660
UniProtQ92552|RT27_HUMAN Small ribosomal subunit protein mS27 (Gene Name=MRPS27)

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