Structure of PDB 8pj5 Chain V

Receptor sequence

>8pj5V (length=189) Species: 9606 (Homo sapiens) [Search protein sequence]

DIKLFGKWSTDDVQINDISLQDYIAVKEKYAKYLPHSAGRYAAKRFRKAQ
CPIVERLTNSMMMHGRNNGKKLMTVRIVKHAFEIIHLLTGENPLQVLVNA
IINSGPREDSTRIGRAGTVRRQAVDVSPLRRVNQAIWLLCTGAREAAFRN
IKTIAECLADELINAAKGSSNSYAIKKKDELERVAKSNR

3D structure

PDB

8pj5 Structural basis for translational control by the human 48S initiation complex from codon scanning toward subunit joining

Chain

Resolution

2.9 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	V	H51 A57 R60 K63 N74 M76 M78 H79 G80 R81 N82 N83 G84 K85 K86 M88 R127 R145 N148 R159 F163 R164 N165 I166 T168 I169	H36 A42 R45 K48 N59 M61 M63 H64 G65 R66 N67 N68 G69 K70 K71 M73 R112 R130 N133 R144 F148 R149 N150 I151 T153 I154
BS02	MG	V	A162 N165 K167	A147 N150 K152

External links

PDB	RCSB:8pj5, PDBe:8pj5, PDBj:8pj5
PDBsum	8pj5
PubMed
UniProt	P46782\|RS5_HUMAN Small ribosomal subunit protein uS7 (Gene Name=RPS5)

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