Structure of PDB 7svt Chain V

Receptor sequence
>7svtV (length=153) Species: 1773 (Mycobacterium tuberculosis) [Search protein sequence]
SADIVGMHYRYPDHYEVEREKIREYAVAVQNDDAWYFEEDGAAELGYKGL
LAPLTFICVFGYKAQAAFFKHANIATAEAQIVQVDQVLKFEKPIVAGDKL
YCDVYVDSVREAHGTQIIVTKNIVTNEEGDLVQETYTTLAGRAGEDGEGF
SDG
3D structure
PDB7svt 1,3-Diarylpyrazolyl-acylsulfonamides Target HadAB/BC Complex in Mycobacterium tuberculosis .
ChainV
Resolution2.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 CI7 V G64 Y65 Q68 T79 I84 V85 Q86 T138 T140 L142 G61 Y62 Q65 T76 I81 V82 Q83 T135 T137 L139
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0016836 hydro-lyase activity
GO:0019171 (3R)-hydroxyacyl-[acyl-carrier-protein] dehydratase activity
Biological Process
GO:0006633 fatty acid biosynthetic process
Cellular Component
GO:0005886 plasma membrane

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:7svt, PDBe:7svt, PDBj:7svt
PDBsum7svt
PubMed36325756
UniProtP9WFK1|Y635_MYCTU UPF0336 protein Rv0635 (Gene Name=Rv0635)

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