Structure of PDB 7rmc Chain V

Receptor sequence
>7rmcV (length=561) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence]
MKYVVVSGGVISGIGKGVLASSTGMLMKTLGLKVTSIKIDPYMNIDAGTM
SPLEHGECFVLDDGGETDLDLGNYERYLGVTLTKDHNITTGKIYSHVIAK
ERKGDYLGKTVQIVPHLTNAIQDWIERVAKIPVDDTGMEPDVCIIELGGT
VGDIESAPFVEALRQFQFKVGKENFALIHVSLVPVIHGEQKTKPTQAAIK
GLRSLGLVPDMIACRCSETLDKPTIDKIAMFCHVGPEQVVNVHDVNSTYH
VPLLLLEQKMIDYLHARLKLDEISLTEEEKQRGLELLSKWKATTGNFDES
METVKIALVGKYTNLKDSYLSVIKALEHSSMKCRRKLDIKWVEATDLEPE
AQESNKTKFHEAWNMVSTADGILIPGGFGVRGTEGMVLAARWARENHIPF
LGVCLGLQIATIEFTRSVLGRKDSHSAEFYPDIDEKNHVVVFMMRLGLRP
TFFQNETEWSQIKKLYGDVSEVHERHRHRYEINPKMVDELENNGLIFVGK
DDTGKRCEILELKNHPYYIATQYHPEYTSKVLDPSKPFLGLVAASAGILQ
DVIEGKYDLEA
3D structure
PDB7rmc Cryo-EM structures of CTP synthase filaments reveal mechanism of pH-sensitive assembly during budding yeast starvation.
ChainV
Resolution3.5 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 6.3.4.2: CTP synthase (glutamine hydrolyzing).
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CTP V D153 I154 E155 D153 I154 E155
BS02 CTP V G13 G15 K16 G17 N73 Y77 L320 K324 G13 G15 K16 G17 N73 Y77 L320 K324
BS03 CTP V K191 T192 K193 K227 K191 T192 K193 K227
BS04 CTP V Q112 V114 Q112 V114
Gene Ontology
Molecular Function
GO:0003883 CTP synthase activity
GO:0005524 ATP binding
GO:0016874 ligase activity
GO:0042802 identical protein binding
Biological Process
GO:0006221 pyrimidine nucleotide biosynthetic process
GO:0006241 CTP biosynthetic process
GO:0006541 glutamine metabolic process
GO:0008654 phospholipid biosynthetic process
GO:0019856 pyrimidine nucleobase biosynthetic process
GO:0044210 'de novo' CTP biosynthetic process
Cellular Component
GO:0000324 fungal-type vacuole
GO:0005737 cytoplasm
GO:0097268 cytoophidium

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7rmc, PDBe:7rmc, PDBj:7rmc
PDBsum7rmc
PubMed34734801
UniProtP28274|URA7_YEAST CTP synthase 1 (Gene Name=URA7)

[Back to BioLiP]