Structure of PDB 6f40 Chain V

Receptor sequence
>6f40V (length=337) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence]
PVCKNCHGTEFERDLSNANNDLVCKACGVVSEDNPIVSELESREATLNNA
RRKLRAVSYALHIPEYITDAAFQWYKLALANNFVQGRRSQNVIASCLYVA
CRKEKTHHMLIDFSSRLQVSVYSIGATFLKMVKKLHITELPLADPSLFIQ
HFAEKLDLADKKIKVVKDAVKLAQRMSKDWMFEGRRPAGIAGACILLACR
MNNLRRTHTEIVAVSHVAEETLQQRLNEFKNTKAAKLSVQKFRENDVEDG
EARPPSFVKNRKKECPRNLHLLPTTDTYLSKVSDDPDNLEDVDDEELNAH
LLNEEASKLKERIWIGLNADFLLEQESKRLKQEADIA
3D structure
PDB6f40 Molecular mechanism of promoter opening by RNA polymerase III.
ChainV
Resolution3.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna V S75 R76 V117 Q118 G119 R120 R121 S122 Y155 S42 R43 V84 Q85 G86 R87 R88 S89 Y122
BS02 dna V R120 R219 A251 E253 T254 R258 R87 R186 A218 E220 T221 R225
Gene Ontology
Molecular Function
GO:0000994 RNA polymerase III core binding
GO:0000995 RNA polymerase III general transcription initiation factor activity
GO:0001006 RNA polymerase III type 3 promoter sequence-specific DNA binding
GO:0001156 TFIIIC-class transcription factor complex binding
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0017025 TBP-class protein binding
GO:0046872 metal ion binding
Biological Process
GO:0001112 DNA-templated transcription open complex formation
GO:0006352 DNA-templated transcription initiation
GO:0006359 regulation of transcription by RNA polymerase III
GO:0006383 transcription by RNA polymerase III
GO:0070897 transcription preinitiation complex assembly
GO:0070898 RNA polymerase III preinitiation complex assembly
Cellular Component
GO:0000126 transcription factor TFIIIB complex
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0097550 transcription preinitiation complex

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Cellular Component
External links
PDB RCSB:6f40, PDBe:6f40, PDBj:6f40
PDBsum6f40
PubMed29345638
UniProtP29056|TF3B_YEAST Transcription factor IIIB 70 kDa subunit (Gene Name=BRF1)

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