Structure of PDB 5vft Chain V

Receptor sequence
>5vftV (length=480) Species: 9606 (Homo sapiens) [Search protein sequence]
PPGGGEQEPPPPPAPQDVEMKEEAATGGGSTGEADGKTAAAAAEHSQREL
DTVTLEDIKEHVKQLEKAVSGKEPRFVLRALRMLPSTSRRLNHYVLYKAV
QGFFTSNNATRDFLLPFLEEPMDTEADLQFRPRTGKAASTPLLPEVEAYL
QLLVVIFMMNSKRYKEAQKISDDLMQKISTQNRRALDLVAAKCYYYHARV
YEFLDKLDVVRSFLHARLRTATLRHDADGQATLLNLLLRNYLHYSLYDQA
EKLVSKSVFPEQANNNEWARYLYYTGRIKAIQLEYSEARRTMTNALRKAP
QHTAVGFKQTVHKLLIVVELLLGEIPDRLQFRQPSLKRSLMPYFLLTQAV
RTGNLAKFNQVLDQFGEKFQADGTYTLIIRLRHNVIKTGVRMISLSYSRI
SLADIAQKLQLDSPEDAEFIVAKAIRDGVIEASINHEKGYVQSKEMIDIY
STREPQLAFHQRISFCLDIHNMSVKAMRFP
3D structure
PDB5vft Structural mechanism for nucleotide-driven remodeling of the AAA-ATPase unfoldase in the activated human 26S proteasome.
ChainV
Resolution7.0 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide V L67 T71 K209 R287 H319 T320 A321 F324 K325 L50 T54 K192 R270 H302 T303 A304 F307 K308
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0030234 enzyme regulator activity
Biological Process
GO:0006511 ubiquitin-dependent protein catabolic process
GO:0042176 regulation of protein catabolic process
GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process
Cellular Component
GO:0000502 proteasome complex
GO:0005576 extracellular region
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005829 cytosol
GO:0005838 proteasome regulatory particle
GO:0008541 proteasome regulatory particle, lid subcomplex
GO:0016020 membrane
GO:0022624 proteasome accessory complex
GO:0032991 protein-containing complex
GO:0034774 secretory granule lumen
GO:0070062 extracellular exosome
GO:1904813 ficolin-1-rich granule lumen

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:5vft, PDBe:5vft, PDBj:5vft
PDBsum5vft
PubMed29636472
UniProtO43242|PSMD3_HUMAN 26S proteasome non-ATPase regulatory subunit 3 (Gene Name=PSMD3)

[Back to BioLiP]