Structure of PDB 4uj3 Chain V

Receptor sequence
>4uj3V (length=169) Species: 9606 (Homo sapiens) [Search protein sequence]
EYDYLFKVVLIGDSGVGKSNLLSRFTRNEFNLESKSTIGVEFATRSIQVD
GKTIKAQIWDTAGLEAITSAYYRGAVGALLVYDIAKHLTYENVERWLKEL
RDHADSNIVIMLVGNKSDLRHLRAVPTDEARAFAEKNGLSFIETSALDST
NVEAAFQTILTEIYRIVSQ
3D structure
PDB4uj3 Structure of Rab11-Fip3-Rabin8 Reveals Simultaneous Binding of Fip3 and Rabin8 Effectors to Rab11.
ChainV
Resolution3.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.5.2: small monomeric GTPase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GNP V S20 G21 G23 K24 S25 N26 F36 L38 S42 T43 K125 D127 L128 S154 A155 L156 S14 G15 G17 K18 S19 N20 F30 L32 S36 T37 K116 D118 L119 S145 A146 L147
BS02 MG V S25 T43 S19 T37
Gene Ontology
Molecular Function
GO:0003924 GTPase activity
GO:0005525 GTP binding

View graph for
Molecular Function
External links
PDB RCSB:4uj3, PDBe:4uj3, PDBj:4uj3
PDBsum4uj3
PubMed26258637
UniProtP62491|RB11A_HUMAN Ras-related protein Rab-11A (Gene Name=RAB11A)

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