Structure of PDB 4csf Chain V

Receptor sequence
>4csfV (length=249) Species: 11590 (Toscana virus) [Search protein sequence]
ENYRDIALAFLDESADSGTINAWVNEFAYQGFDPKRIVQLVKERGTAKGR
DWKKDVKMMIVLNLVRGNKPEAMMKKMSEKGASIVANLISVYQLKEGNPG
RDTITLSRVSAAFVPWTVQALRVLSESLPVSGTTMDAIAGVTYPRAMMHP
SFAGIIDLDLPNGAGATIADAHGLFMIEFSKTINPSLRTKQANEVAATFE
KPNMAAMSGRFFTREDKKKLLIAVGIIDEDLVLASAVVRSAEKYRAKVG
3D structure
PDB4csf Structural Insights Into RNA Encapsidation and Helical Assembly of the Toscana Virus Nucleoprotein.
ChainV
Resolution2.598 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna V Y32 K204 Y29 K201 PDBbind-CN: Kd=260nM
BS02 rna V K79 T185 I186 K76 T182 I183 PDBbind-CN: Kd=260nM
Gene Ontology
Cellular Component
GO:0019013 viral nucleocapsid
GO:0019029 helical viral capsid
GO:0030430 host cell cytoplasm
GO:0042025 host cell nucleus
GO:0044172 host cell endoplasmic reticulum-Golgi intermediate compartment
GO:0044177 host cell Golgi apparatus
GO:1990904 ribonucleoprotein complex

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Molecular Function
View graph for
Cellular Component
External links
PDB RCSB:4csf, PDBe:4csf, PDBj:4csf
PDBsum4csf
PubMed24688060
UniProtP21701|NCAP_TOSV Nucleoprotein (Gene Name=N)

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