Structure of PDB 4a2i Chain V

Receptor sequence

>4a2iV (length=277) Species: 90371 (Salmonella enterica subsp. enterica serovar Typhimurium)

LFGEPAEGIVISRFGMHADVESADGEVHRCNIRRTIRSLVTGDRVVWRPG
KVKGIVEAVHETSVLTRPVKPIAANIDQIVIVSAILPELSLNIIDRYLVG
CETLQVEPLIVLNKIDLLDDEGMDFVNEQMDIYRNIGYRVLMVSSHTQDG
LKPLEEALTGRISIFAGQSGVGKSSLLNALLGLQNEILTNTAARLYHFPH
GGDVIDSPGVREFGLWHLEPEQITQGFVEFHDYLGHCKYRDCKHDADPGC
AIREAVENGAIAETRFENYHRILESMA

3D structure

• PDB: 4a2i Cryo-Electron Microscopy Structure of the 30S Subunit in Complex with the Yjeq Biogenesis Factor.
• Chain: V
• Resolution: 16.5 Å

Enzymatic activity

• Enzyme Commision number: 3.6.1.-

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	V	F56 M58 H59 A60 D61 V62 V69 H70 R71 C72 K102 R117 P118 V124 K125 N147 R151 L283 W284 H285 L286 E287 P288 E289 I291 T292 Q293 F295 F298 L302 K306 Y307 R308 D309 C310 K311 H312 D313 A314 D315 P316 I320 R333 F334 E335 N336 Y337 H338 R339 I340 L341 E342 S343 M344 A345	F14 M16 H17 A18 D19 V20 V27 H28 R29 C30 K53 R67 P68 V69 K70 N92 R96 L215 W216 H217 L218 E219 P220 E221 I223 T224 Q225 F227 F230 L234 K238 Y239 R240 D241 C242 K243 H244 D245 A246 D247 P248 I252 R265 F266 E267 N268 Y269 H270 R271 I272 L273 E274 S275 M276 A277

Gene Ontology

Molecular Function

• GO:0003924 GTPase activity
• GO:0005525 GTP binding

External links

• PDB: RCSB:4a2i, PDBe:4a2i, PDBj:4a2i
• PDBsum: 4a2i
• PubMed: 21960487
• UniProt: Q8ZKB0|RSGA_SALTY Small ribosomal subunit biogenesis GTPase RsgA (Gene Name=rsgA)