Structure of PDB 3unf Chain V

Receptor sequence
>3unfV (length=219) Species: 10090 (Mus musculus) [Search protein sequence]
TTIAGLVFRDGVILGADTRATNDSVVADKSCEKIHFIAPKIYCCGAGVAA
DTEMTTRMAASKMELHALSTGREPRVATVTRILRQTLFRYQGHVGASLVV
GGVDLNGPQLYEVHPHGSYSRLPFTALGSGQGAAVALLEDRFQPNMTLEA
AQELLVEAITAGILSDLGSGGNVDACVITAGGAKLQRALSTPTEPVQRAG
RYRFAPGTTPVLTREVRPL
3D structure
PDB3unf Immuno- and constitutive proteasome crystal structures reveal differences in substrate and inhibitor specificity.
ChainV
Resolution2.9 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) T1 D17 R19 K33 G47 S129 D166 S169
Catalytic site (residue number reindexed from 1) T1 D17 R19 K33 G47 S129 D166 S169
Enzyme Commision number 3.4.25.1: proteasome endopeptidase complex.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 04C V T1 A20 T21 N22 G47 V48 A49 T52 G168 T1 A20 T21 N22 G47 V48 A49 T52 G168
Gene Ontology
Molecular Function
GO:0004298 threonine-type endopeptidase activity
Biological Process
GO:0051603 proteolysis involved in protein catabolic process
Cellular Component
GO:0005839 proteasome core complex

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Cellular Component
External links
PDB RCSB:3unf, PDBe:3unf, PDBj:3unf
PDBsum3unf
PubMed22341445
UniProtO35955|PSB10_MOUSE Proteasome subunit beta type-10 (Gene Name=Psmb10)

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