Structure of PDB 3j7o Chain V

Receptor sequence
>3j7oV (length=131) Species: 9823 (Sus scrofa) [Search protein sequence]
SGAKFRISLGLPVGAVINCADNTGAKNLYIISVKGIKGRLNRLPAAGVGD
MVMATVKKGKPELRKKVHPAVVIRQRKSYRRKDGVFLYFEDNAGVIVNNK
GEMKGSAITGPVAKECADLWPRIASNAGSIA
3D structure
PDB3j7o Structure of the Mammalian ribosome-sec61 complex to 3.4 a resolution.
ChainV
Resolution3.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna V S10 G11 A12 K13 F14 R15 S17 G19 P21 A24 V25 I40 S41 G44 I45 K46 G47 R48 L49 N50 R51 L52 M62 T64 V76 R85 K86 R89 F95 S1 G2 A3 K4 F5 R6 S8 G10 P12 A15 V16 I31 S32 G35 I36 K37 G38 R39 L40 N41 R42 L43 M53 T55 V67 R76 K77 R80 F86
Gene Ontology
Molecular Function
GO:0001223 transcription coactivator binding
GO:0003735 structural constituent of ribosome
GO:0031625 ubiquitin protein ligase binding
GO:0070180 large ribosomal subunit rRNA binding
GO:1990948 ubiquitin ligase inhibitor activity
Biological Process
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0006412 translation
GO:0008284 positive regulation of cell population proliferation
GO:0010628 positive regulation of gene expression
GO:0032986 protein-DNA complex disassembly
GO:0050821 protein stabilization
GO:0070314 G1 to G0 transition
GO:0072717 cellular response to actinomycin D
GO:1901798 positive regulation of signal transduction by p53 class mediator
GO:1903450 regulation of G1 to G0 transition
GO:1904667 negative regulation of ubiquitin protein ligase activity
GO:2000059 negative regulation of ubiquitin-dependent protein catabolic process
Cellular Component
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005840 ribosome
GO:0015934 large ribosomal subunit
GO:0022625 cytosolic large ribosomal subunit
GO:0022626 cytosolic ribosome
GO:0032991 protein-containing complex
GO:0045202 synapse
GO:0098556 cytoplasmic side of rough endoplasmic reticulum membrane
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3j7o, PDBe:3j7o, PDBj:3j7o
PDBsum3j7o
PubMed24930395
UniProtP62831|RL23_PIG Large ribosomal subunit protein uL14 (Gene Name=RPL23)

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