Structure of PDB 1lm8 Chain V

Receptor sequence
>1lm8V (length=150) Species: 9606 (Homo sapiens) [Search protein sequence]
RPVLRSVNSREPSQVIFCNRSPRVVLPVWLNFDGEPQPYPTLPPGTGRRI
HSYRGHLWLFRDAGTHDGLLVNQTELFVPSLNVDGQPIFANITLPVYTLK
ERCLQVVRSLVKPENYRRLDIVRSLYEDLEDHPNVQKDLERLTQERIAHQ
3D structure
PDB1lm8 Structure of an HIF-1alpha -pVHL complex: hydroxyproline recognition in signaling.
ChainV
Resolution1.85 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide V N67 N78 W88 F91 Y98 P99 G104 T105 G106 R107 R108 I109 H110 S111 Y112 H115 W117 N8 N19 W29 F32 Y39 P40 G45 T46 G47 R48 R49 I50 H51 S52 Y53 H56 W58
External links
PDB RCSB:1lm8, PDBe:1lm8, PDBj:1lm8
PDBsum1lm8
PubMed12004076
UniProtP40337|VHL_HUMAN von Hippel-Lindau disease tumor suppressor (Gene Name=VHL)

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