Structure of PDB 7aju Chain UM

Receptor sequence
>7ajuUM (length=762) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence]
YKGISLNPIYAGSSAVATVSENGKILATPVLDEINIIDLTPGSRKILHKI
SNEDEQEITALKLTPDGQYLTYVSQAQLLKIFHLKTGKVVRSMKISSPSY
ILDADSTSTLLAVGGTDGSIIVVDIENGYITHSFKGHGGTISSLKFYGQL
NSKIWLLASGDTNGMVKVWDLVKRKCLHTLQEHTSAVRGLDIIEVLNLLS
GGRDDIINLWDFNMKKKCKLLKTLPVNQQVESCGFLKDGDGKRIIYTAGG
DAIFQLIDSESGSVLKRTNKPIEELFIIGVLPILSNSQMFLVLSDQTLQL
INVEDTIQVTSSIAGNHGIIADMRYVGPELNKLALATNSPSLRIIPVPLP
LDVEIYEGHEDLLNSLDATEDGLWIATASKDNTAIVWRYNENSCKFDIYA
KYIGHSAAVTAVGLPNIVSKGYPEFLLTASNDLTIKKWIITRHAHEKDIN
ALSVSPNDSIFATASYDKTCKIWNLENGELEATLANHKRGLWDVSFCQYD
KLLATSSGDKTVKIWSLDTFSVMKTLEGHTNAVQRCSFINKQKQLISCGA
DGLIKIWDCSSGECLKTLDGHNNRLWALSTMNDGDMIVSADADGVFQFWK
DCEQEIEEEQEKAKLQVEQEQSLQNYMSKGDWTNAFLLAMTLDHPMRLFN
VLKRALGESRSEVIFNEELDQAISILNDEQLILLMKRCRDWNTNAKTHTI
AQRTIRCILMHHNIAKLSEIPGMVKIVDAIIPYTQRHFTRVDNLVEQSYI
LDYALVEMDKLF
3D structure
PDB7aju Structure of the Maturing 90S Pre-ribosome in Association with the RNA Exosome.
ChainUM
Resolution3.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna UM K408 R534 N749 A750 K751 R795 K380 R489 N694 A695 K696 R740
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0034511 U3 snoRNA binding
Biological Process
GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000472 endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0006364 rRNA processing
GO:0030490 maturation of SSU-rRNA
GO:0042254 ribosome biogenesis
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0030686 90S preribosome
GO:0032040 small-subunit processome
GO:0034388 Pwp2p-containing subcomplex of 90S preribosome
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7aju, PDBe:7aju, PDBj:7aju
PDBsum7aju
PubMed33326748
UniProtQ05946|UTP13_YEAST U3 small nucleolar RNA-associated protein 13 (Gene Name=UTP13)

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