Structure of PDB 6zqf Chain UL

Receptor sequence
>6zqfUL (length=777) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence]
YQRFEQAAAFGVIASNANCVWIPAPGQLITSALEDVNIWDIKTGDLVSKL
SDGLPPGASDARGAKPAECTYLEAHKDTDLLAVGYADGVIKVWDLMSKTV
LLNFNGHKAAITLLQFDGTGTRLISGSKDSNIIVWDLVGEVGLYKLRSHK
DSITGFWCQGEDWLISTSKDGMIKLWDLKTHQCIETHIAHTGECWGLAVK
DDLLITTGTDSQVKIWKLDIENDKMGGKLTEMGIFEKQSKQRGLKIEFIT
NSFFYIQNADKTIETFRIYSSFILHPFQTIRSLYKIKSASWTTVSSSKLE
LVLTTSSNTIEYYSIPYEKRDPTSPAPLKTHTIELQGQRTDVRSIDISDD
NKLLATASNGSLKIWNIKTHKCIRTFECGYALTCKFLPGGLLVILGTRNG
ELQLFDLASSSLLDTIEDAHDAAIWSLDLTSDGKRLVTGSADKTVKFWDF
KVLKLHHDTTLELTDDILCVRVSPDDRYLAISLLDNTVKVFFLDSMKFYL
SLYGHKLPVLSIDISFDSKMIITSSADKNIKIWGLDFGDCHKSLFAHQDS
IMNVKFLPQSHNFFSCSKDAVVKYWDGEKFECIQKLYAHQSEVWALAVAT
DGGFVVSSSHDHSIRIWEETSLKAGERLMEALDLGIAEIEGLEAYNRDMK
AVLIAVNKTPEQYIMDTLLRIRMSQLEDALMVMPFSYVLKFLKFIDTVMQ
NKTLLHSHLPLICKNLFFIIKFNHKELVSQKNEELKLQINRVKTELRSAL
KSTEDDLGFNVQGLKFVKQQWNLRHNY
3D structure
PDB6zqf 90 S pre-ribosome transformation into the primordial 40 S subunit.
ChainUL
Resolution4.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna UL K163 D164 K150 D151
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0030515 snoRNA binding
GO:0034511 U3 snoRNA binding
Biological Process
GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000472 endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0006364 rRNA processing
GO:0030490 maturation of SSU-rRNA
GO:0042254 ribosome biogenesis
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0030686 90S preribosome
GO:0032040 small-subunit processome
GO:0034388 Pwp2p-containing subcomplex of 90S preribosome
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6zqf, PDBe:6zqf, PDBj:6zqf
PDBsum6zqf
PubMed32943521
UniProtQ12220|UTP12_YEAST U3 small nucleolar RNA-associated protein 12 (Gene Name=DIP2)

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