Structure of PDB 6zqd Chain UG

Receptor sequence
>6zqdUG (length=470) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence]
QTKDKKLRAGLKKIDEQYKKAVSSAAATDYLLPESNGYLEPENELEKTFK
VQQSEIKSSVDVSTANKALDLSLKEFGPYHIKYAKNGTHLLITGRKGHVA
SMDWRKGQLRAELFLNETCHSATYLQNEQYFAVAQKKYTFIYDHEGTELH
RLKQHIEARHLDFLPYHYLLVTAGETGWLKYHDVSTGQLVSELRTKAGPT
MAMAQNPWNAVMHLGHSNGTVSLWSPSMPEPLVKLLSARGPVNSIAIDRS
GYYMATTGADRSMKIWDIRNFKQLHSVESLPTPGTNVSISDTGLLALSRG
PHVTLWKDALKLSGDSKPCFGSMGGNPHRNTPYMSHLFAGNKVENLGFVP
FEDLLGVGHQTGITNLIVPGAGEANYDALELNPFETKKQRQEQEVRTLLN
KLPADTITLDPNSIGSVDKRSGLRSFLRKKTQNVIDERKLRVQKQLDKEK
NIRKRNHQIDVIEEALSRFG
3D structure
PDB6zqd 90 S pre-ribosome transformation into the primordial 40 S subunit.
ChainUG
Resolution3.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 rna UG H179 K422 H144 K387
BS02 rna UG G496 F500 L501 R502 K504 E511 R512 K518 G422 F426 L427 R428 K430 E437 R438 K444
BS03 rna UG L414 K423 R431 L379 K388 R396
Gene Ontology
Molecular Function
GO:0003674 molecular_function
GO:0005515 protein binding
Biological Process
GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000472 endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0006364 rRNA processing
GO:0030490 maturation of SSU-rRNA
GO:0042254 ribosome biogenesis
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0030686 90S preribosome
GO:0030688 preribosome, small subunit precursor
GO:0032040 small-subunit processome
GO:1990904 ribonucleoprotein complex

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:6zqd, PDBe:6zqd, PDBj:6zqd
PDBsum6zqd
PubMed32943521
UniProtP40055|UTP7_YEAST U3 small nucleolar RNA-associated protein 7 (Gene Name=UTP7)

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