Structure of PDB 8sf7 Chain UC

Receptor sequence
>8sf7UC (length=431) Species: 5911 (Tetrahymena thermophila) [Search protein sequence]
MREVISIHVGQGGIQVGNACWELFCLEHGIQPDGQMPSDAFNTFFSETGA
GKHVPRAVFLDLEPTVIDEVRTGTYRQLFHPEQLISGKEDAANNFARGHY
TIGKEIVDLCLDRIRKLADNCTGLQGFLVFNSVGGGTGSGLGSLLLERLS
VDYGKKSKLGFTIYPSPQVSTAVVEPYNSILSTHSLLEHTDVAVMLDNEA
IYDICRRNLDIERPTYTNLNRLIAQVISSLTASLRFDGALNVDITEFQTN
LVPYPRIHFMLSSYAPIISAEKAYHEQLSVAEITNSAFEPANMMAKCDPR
HGKYMACSMMYRGDVVPKDVNASIATIKTKRTIQFVDWCPTGFKVGINYQ
PPTVVPGGDLAKVMRAVCMISNSTAIAEVFSRLDHKFDLMYAKRAFVHWY
VGEGMEEGEFSEAREDLAALEKDYEEVGIET
3D structure
PDB8sf7 Effect of alpha-tubulin acetylation on the doublet microtubule structure
ChainUC
Resolution4.1 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 3.6.5.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GTP UC G10 Q11 G12 Q15 N101 S140 G143 G144 T145 G146 T179 N206 Y224 G10 Q11 G12 Q15 N93 S132 G135 G136 T137 G138 T171 N198 Y216
Gene Ontology
Molecular Function
GO:0005200 structural constituent of cytoskeleton
GO:0005525 GTP binding
GO:0016787 hydrolase activity
GO:0046872 metal ion binding
Biological Process
GO:0000226 microtubule cytoskeleton organization
GO:0000278 mitotic cell cycle
Cellular Component
GO:0005737 cytoplasm
GO:0005856 cytoskeleton
GO:0005874 microtubule

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:8sf7, PDBe:8sf7, PDBj:8sf7
PDBsum8sf7
PubMed38598282
UniProtP41351|TBA_TETTH Tubulin alpha chain

[Back to BioLiP]