Structure of PDB 8kd5 Chain U

Receptor sequence
>8kd5U (length=107) Species: 8355 (Xenopus laevis) [Search protein sequence]
RAKAKTRSSRAGLQFPVGRVHRLLRKGNYAERVGAGAPVYLAAVLEYLTA
EILELAGNAARDNKKTRIIPRHLQLAVRNDEELNKLLGRVTIAQGGVLPN
IQSVLLP
3D structure
PDB8kd5 Structural basis of nucleosome deacetylation and DNA linker tightening by Rpd3S histone deacetylase complex.
ChainU
Resolution2.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 dna U R11 A12 K15 R17 G28 R32 R1 A2 K5 R7 G18 R22
BS02 dna U A14 R29 E41 R42 V43 G44 A45 K75 T76 R77 A4 R19 E31 R32 V33 G34 A35 K65 T66 R67
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0030527 structural constituent of chromatin
GO:0046982 protein heterodimerization activity
Cellular Component
GO:0000786 nucleosome
GO:0005634 nucleus
GO:0005694 chromosome

View graph for
Molecular Function

View graph for
Cellular Component
External links
PDB RCSB:8kd5, PDBe:8kd5, PDBj:8kd5
PDBsum8kd5
PubMed37666978
UniProtP06897|H2A1_XENLA Histone H2A type 1

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