Structure of PDB 8imy Chain U

Receptor sequence
>8imyU (length=419) Species: 9606 (Homo sapiens) [Search protein sequence]
AAPLVLVLVVAVTVRAALFRSSLAEFISERVEVVSPLSSWKRVVEGLSLL
DLGVSPYSGAVFHETPLIIYLFHFLIDYAELVFMITDALTAIALYFAIQD
FNKVVFKKQKLLLELDQYAPDVAELIRTPMEMRYIPLKVALFYLLNPYTI
LSCVAKSTCAINNTLIAFFILTTIKGSAFLSAIFLALATYQSLYPLTLFV
PGLLYLLQRQYIPVKMKSKAFWIFSWEYAMMYVGSLVVIICLSFFLLSSW
DFIPAVYGFILSVPDLTPNIGLFWYFFAEMFEHFSLFFVCVFQINVFFYT
IPLAIKLKEHPIFFMFIQIAVIAIFKSYPTVGDVALYMAFFPVWNHLYRF
LRNIFVLTCIIIVCSLLFPVLWHLWIYAGSANSNFFYAITLTFNVGQILL
ISDYFYAFLRREYYLTHGL
3D structure
PDB8imy Structures of substrates- and products-bound glycosylphosphatidylinositol transamidase illuminate GPI-AP biogenesis
ChainU
Resolution3.22 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0034235 GPI anchor binding
Biological Process
GO:0006091 generation of precursor metabolites and energy
GO:0006506 GPI anchor biosynthetic process
GO:0008218 bioluminescence
GO:0016255 attachment of GPI anchor to protein
GO:0046425 regulation of receptor signaling pathway via JAK-STAT
Cellular Component
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0042765 GPI-anchor transamidase complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8imy, PDBe:8imy, PDBj:8imy
PDBsum8imy
PubMed37684232
UniProtQ9H490|PIGU_HUMAN Phosphatidylinositol glycan anchor biosynthesis class U protein (Gene Name=PIGU)

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