Structure of PDB 7wps Chain U

Receptor sequence
>7wpsU (length=711) Species: 9606 (Homo sapiens) [Search protein sequence]
SSTARCSLFGSDFVNTFDGSMYSFAGYCSYLLAGGCQKRSFSIIGDFQNG
KRVSLSVYLGEFFDIHLFVNGTVTQGDQRVSMPYASKGLYLETEAGYYKL
SGEAYGFVARIDGSGNFQVLLSDRYFNKTCGLCGNFNIFAEDDFMTQEGT
LTSDPYDFANSWALSSGEQWCERASPPSSSCNISSGEMQKGLWEQCQLLK
STSVFARCHPLVDPEPFVALCEKTLCECAGGLECACPALLEYARTCAQEG
MVLYGWTDHSACSPVCPAGMEYRQCVSPCARTCQSLHINEMCQERCVDGC
SCPEGQLLDEGLCVESTECPCVHSGKRYPPGTSLSRDCNTCICRNSQWIC
SNEECPGECLVTGQSHFKSFDNRYFTFSGICQYLLARDCQDHSFSIVIET
VQCADDRDAVCTRSVTVRLPGLHNSLVKLKHGAGVAMDGQDVQLPLLKGD
LRIQHTVTASVRLSYGEDLQMDWDGRGRLLVKLSPVYAGKTCGLCGNYNG
NQGDDFLTPSGLAEPRVEDFGNAWKLHGDCQDLQKQHSDPCALNPRMTRF
SEEACAVLTSPTFEACHRAVSPLPYLRNCRYDVCSCSDGRECLCGALASY
AAACAGRGVRVAWREPGRCELNCPKGQVYLQCGTPCNLTCRSLSYPDEEC
NEACLEGCFCPPGLYMDERGDCVPKAQCPCYYDGEIFQPEDIFSDHHTMC
YCEDGFMHCTM
3D structure
PDB7wps Structural basis of von Willebrand factor multimerization and tubular storage.
ChainU
Resolution4.32 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 CA U D47 N164 N166 F168 D172 D18 N135 N137 F139 D143
BS02 CA U D400 N526 N528 N530 D533 D534 D371 N497 N499 N501 D504 D505
External links
PDB RCSB:7wps, PDBe:7wps, PDBj:7wps
PDBsum7wps
PubMed35148377
UniProtP04275|VWF_HUMAN von Willebrand factor (Gene Name=VWF)

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