Structure of PDB 7pfv Chain U

Receptor sequence
>7pfvU (length=75) Species: 9606 (Homo sapiens) [Search protein sequence]
SGPPVSELITKAVAASKERSGVSLAALKKALAAAGYDVEKNNSRIKLGLK
SLVSKGTLVQTKGTGASGSFKLNKK
3D structure
PDB7pfv Histone H1 binding to nucleosome arrays depends on linker DNA length and trajectory.
ChainU
Resolution4.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 dna U P38 V39 R53 S57 K63 R78 K96 S101 G102 S103 P4 V5 R19 S23 K29 R44 K62 S67 G68 S69
BS02 dna U L58 K62 K80 T98 A100 S101 L24 K28 K46 T64 A66 S67
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003690 double-stranded DNA binding
GO:0003723 RNA binding
GO:0005515 protein binding
GO:0030527 structural constituent of chromatin
GO:0031490 chromatin DNA binding
GO:0031492 nucleosomal DNA binding
GO:0042826 histone deacetylase binding
Biological Process
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0006325 chromatin organization
GO:0006334 nucleosome assembly
GO:0006357 regulation of transcription by RNA polymerase II
GO:0030261 chromosome condensation
GO:0045910 negative regulation of DNA recombination
Cellular Component
GO:0000786 nucleosome
GO:0000791 euchromatin
GO:0000792 heterochromatin
GO:0005634 nucleus
GO:0005694 chromosome

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:7pfv, PDBe:7pfv, PDBj:7pfv
PDBsum7pfv
PubMed35581345
UniProtP10412|H14_HUMAN Histone H1.4 (Gene Name=H1-4)

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