Structure of PDB 7pfa Chain U

Receptor sequence

>7pfaU (length=75) Species: 9606 (Homo sapiens) [Search protein sequence]

SGPPVSELITKAVAASKERSGVSLAALKKALAAAGYDVEKNNSRIKLGLK
SLVSKGTLVQTKGTGASGSFKLNKK

3D structure

PDB

7pfa Histone H1 binding to nucleosome arrays depends on linker DNA length and trajectory.

Chain

Resolution

9.7 Å

3D
structure

Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	dna	U	L58 K62 N76 K80 K84 T98 G99 A100	L24 K28 N42 K46 K50 T64 G65 A66
BS02	dna	U	V39 G55 S57 R78 K96 G97 S101 G102 S103	V5 G21 S23 R44 K62 G63 S67 G68 S69

Gene Ontology

	Molecular Function
GO:0003677	DNA binding
GO:0003690	double-stranded DNA binding
GO:0003723	RNA binding
GO:0005515	protein binding
GO:0030527	structural constituent of chromatin
GO:0031490	chromatin DNA binding
GO:0031492	nucleosomal DNA binding
GO:0042826	histone deacetylase binding

	Biological Process
GO:0000122	negative regulation of transcription by RNA polymerase II
GO:0006325	chromatin organization
GO:0006334	nucleosome assembly
GO:0006357	regulation of transcription by RNA polymerase II
GO:0030261	chromosome condensation
GO:0045910	negative regulation of DNA recombination

External links