Structure of PDB 7lvk Chain U

Receptor sequence

>7lvkU (length=136) Species: 562 (Escherichia coli) [Search protein sequence]

MLQPKRTKFRKMHKGRNRGLAQGTDVSFGSFGLKAVGRGRLTARQIEAAR
RAMTRAVKRQGKIWIRVFPDKPITEKPLAVRMGKGKGNVEYWVALIQPGK
VLYEMDGVPEELAREAFKLAAAKLPIKTTFVTKTVM

3D structure

PDB

7lvk Investigating antibiotic resistance of a ribosomal-RNA methylating enzyme through directed evolution

Chain

Resolution

2.2 Å

3D
structure

Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	U	K5 R6 K8 F9 K11 H13 K14 G15 R16 N17 Q22 G23 F28 R40 R44 Q45 A48 K62 W64 R66 F68 D70 E75 K76 L78 A79 X81 M82 G83 K84 G85 K86 K100 A122 K123 P125 K127	K5 R6 K8 F9 K11 H13 K14 G15 R16 N17 Q22 G23 F28 R40 R44 Q45 A48 K62 W64 R66 F68 D70 E75 K76 L78 A79 X81 M82 G83 K84 G85 K86 K100 A122 K123 P125 K127
BS02	rna	U	R16 N17 R18 G19 R38	R16 N17 R18 G19 R38

Gene Ontology

	Molecular Function
GO:0000049	tRNA binding
GO:0003735	structural constituent of ribosome
GO:0019843	rRNA binding

	Biological Process
GO:0000027	ribosomal large subunit assembly
GO:0002181	cytoplasmic translation
GO:0006412	translation

	Cellular Component
GO:0005737	cytoplasm
GO:0005840	ribosome
GO:0022625	cytosolic large ribosomal subunit
GO:1990904	ribonucleoprotein complex

External links

PDB	RCSB:7lvk, PDBe:7lvk, PDBj:7lvk
PDBsum	7lvk
PubMed
UniProt	P0ADY7\|RL16_ECOLI Large ribosomal subunit protein uL16 (Gene Name=rplP)