Structure of PDB 6yan Chain U

Receptor sequence

>6yanU (length=142) Species: 9986 (Oryctolagus cuniculus)

PEKFQHILRVLNTNIDGRRKIAFAITAIKGVGRRYAHVVLRKADIDLTKR
AGELTEDEVERVITIMQNPRQYKIPDWFLNRQKDVKDGKYSQVLANGLDN
KLREDLERLKKIRAHRGLRHFWGLRVRGQHTKTTGRRGRTVG

3D structure

• PDB: 6yan Structural Insights into the Mammalian Late-Stage Initiation Complexes.
• Chain: U
• Resolution: 3.48 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	U	K25 F28 K34 G35 V36 G37 R38 R39 Y40 W82 F83 L84 N85 R86 Q87 L107 H120 R121 R124 R130 R132 G133 Q134 H135 T136 K137 T138 T139 R141 R142 G143 R144 T145 V146	K20 F23 K29 G30 V31 G32 R33 R34 Y35 W77 F78 L79 N80 R81 Q82 L102 H115 R116 R119 R125 R127 G128 Q129 H130 T131 K132 T133 T134 R136 R137 G138 R139 T140 V141

Gene Ontology

Molecular Function

• GO:0003676 nucleic acid binding
• GO:0003723 RNA binding
• GO:0003735 structural constituent of ribosome
• GO:0019843 rRNA binding

Biological Process

• GO:0006412 translation

Cellular Component

• GO:0005737 cytoplasm
• GO:0005829 cytosol
• GO:0005840 ribosome
• GO:0015935 small ribosomal subunit
• GO:0022626 cytosolic ribosome
• GO:1990904 ribonucleoprotein complex

External links

• PDB: RCSB:6yan, PDBe:6yan, PDBj:6yan
• PDBsum: 6yan
• PubMed: 32268096
• UniProt: G1TPG3|RS18_RABIT Small ribosomal subunit protein uS13 (Gene Name=RPS18)