Structure of PDB 6qvj Chain U

Receptor sequence
>6qvjU (length=430) Species: 9606 (Homo sapiens) [Search protein sequence]
MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGTYHGDSDLQLDRISVY
YNEATGGKYVPRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNN
WAKGHYTEGAELVDSVLDVVRKEAESCDCLQGFQLTHSLGGGTGSGMGTL
LISKIREEYPDRIMNTFSVVPSPKVSDTVVEPYNATLSVHQLVENTDETY
CIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADL
RKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQVFDAKNMM
AACDPRHGRYLTVAAVFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVK
TAVCDIPPRGLKMAVTFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTG
EGMDEMEFTEAESNMNDLVSEYQQYQDATA
3D structure
PDB6qvj Structural determinants of microtubule minus end preference in CAMSAP CKK domains.
ChainU
Resolution3.8 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GDP U Q11 C12 G143 G144 T145 G146 N206 Y224 N228 Q11 C12 G141 G142 T143 G144 N204 Y222 N226
BS02 TA1 U H229 A233 S236 T276 R278 R369 L371 H227 A231 S234 T274 R276 R359 L361
Gene Ontology
Molecular Function
GO:0003924 GTPase activity
GO:0005198 structural molecule activity
GO:0005200 structural constituent of cytoskeleton
GO:0005515 protein binding
GO:0005525 GTP binding
GO:0019904 protein domain specific binding
GO:0031625 ubiquitin protein ligase binding
GO:0032794 GTPase activating protein binding
GO:0042288 MHC class I protein binding
GO:0044877 protein-containing complex binding
GO:0046872 metal ion binding
Biological Process
GO:0000226 microtubule cytoskeleton organization
GO:0000278 mitotic cell cycle
GO:0007017 microtubule-based process
GO:0030705 cytoskeleton-dependent intracellular transport
GO:0042267 natural killer cell mediated cytotoxicity
GO:0050807 regulation of synapse organization
GO:0051225 spindle assembly
GO:0051301 cell division
GO:0071895 odontoblast differentiation
Cellular Component
GO:0005576 extracellular region
GO:0005634 nucleus
GO:0005641 nuclear envelope lumen
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005856 cytoskeleton
GO:0005874 microtubule
GO:0015630 microtubule cytoskeleton
GO:0032991 protein-containing complex
GO:0035578 azurophil granule lumen
GO:0036464 cytoplasmic ribonucleoprotein granule
GO:0044297 cell body
GO:0045121 membrane raft
GO:0045171 intercellular bridge
GO:0070062 extracellular exosome
GO:0072686 mitotic spindle

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:6qvj, PDBe:6qvj, PDBj:6qvj
PDBsum6qvj
PubMed31748546
UniProtP07437|TBB5_HUMAN Tubulin beta chain (Gene Name=TUBB)

[Back to BioLiP]