Structure of PDB 6lab Chain U

Receptor sequence
>6labU (length=104) Species: 9606 (Homo sapiens) [Search protein sequence]
KPKRAKASKKSTDHPKYSDMIVAAIQAEKNRAGSSRQSIQKYIKSHYKVG
ENADSQIKLSIKRLVTTGVLKQTKGVGASGSFRLAKSDEPKKSVAFKKTK
KEIK
3D structure
PDB6lab Engineering nucleosomes for generating diverse chromatin assemblies.
ChainU
Resolution3.2 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 dna U H57 E62 H46 E51
BS02 dna U K52 Y53 K41 Y42
BS03 dna U P101 K102 K103 P90 K91 K92
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003680 minor groove of adenine-thymine-rich DNA binding
GO:0003690 double-stranded DNA binding
GO:0003723 RNA binding
GO:0005515 protein binding
GO:0030527 structural constituent of chromatin
GO:0031490 chromatin DNA binding
GO:0031491 nucleosome binding
GO:0031492 nucleosomal DNA binding
Biological Process
GO:0006334 nucleosome assembly
GO:0030261 chromosome condensation
GO:0031507 heterochromatin formation
GO:0045910 negative regulation of DNA recombination
GO:2000679 positive regulation of transcription regulatory region DNA binding
Cellular Component
GO:0000785 chromatin
GO:0000786 nucleosome
GO:0000791 euchromatin
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005694 chromosome
GO:0005794 Golgi apparatus
GO:0015629 actin cytoskeleton
GO:0016604 nuclear body
GO:0017053 transcription repressor complex

View graph for
Molecular Function

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:6lab, PDBe:6lab, PDBj:6lab
PDBsum6lab
PubMed33590100
UniProtP07305|H10_HUMAN Histone H1.0 (Gene Name=H1-0)

[Back to BioLiP]